January 23, 2018
methyl-DNAshape Query Tables

Rao et al. Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein-DNA binding.
Epigenetics & Chromatin In press (2018)

DESCRIPTION
For the analysis of human Pbx-Hox complexes, the methylated-DNA table (mPQT) and unmethylated-DNA table (PQT) do not capture a weak dependency of shape on the sixth position, which confounds the estimate of the methylation effect on shape. Here we complied an additional table consisting of unmethylated-DNA shape parameters for all hexamers ending with CpG and heptamers with CpG flanks, which we used to estimate the effect of methylation on shape.

 

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Methylated Pentamer Query Table download

Additional Methylated Query Table download